Intracranial abscesses are the result of an infection that
occurs when bacteria and certain types of fungi gain entry to the tissues of
the brain.
The presence of bacteria and fungi in the brain leads to the formation
of pockets of pus that are filled with dead and live bacteria. The formation of
these pus pockets result in areas of swelling and pressure in and around the
areas affected by the infection.
Without treatment the pus pockets begin to swell causing inflammation
of brain tissue, progressive swelling and pressure on other structures of the
brain. Abscess formation in the brain can lead to devastating complications
which could ultimately result in stroke, hemorrhage, or other serious injury
including death.
Antibiotics are used for treatment but they may not penetrate
well into brain abscesses. Furthermore, white blood cells, which kill infecting
bacteria, may not have enough oxygen to effectively eliminate the infection if
they are functioning deep in the abscess at a distance from their normal blood
supply. White blood cells require a minimum level of oxygen to kill bacteria.
The goal of treating an intracranial
abscess by hyperbaric oxygen therapy is to reduce swelling in the brain by
treating the infection and ultimately shrinking the abscessed tissue.
Hyperbaric oxygen therapy (HBOT) is approved as an adjunct
treatment to surgery, antibiotic and antifungal treatment.
The fungi and bacteria involved in the infection of brain tissue
are anaerobic bacteria which means that they do not survive well in
environments that contain high levels of oxygen. As a result, Hyperbaric Oxygen
Therapy (HBOT) provides an additional layer of antimicrobial protection by
mounting a direct assault on the bacteria and fungi responsible to the abscess
formation. The high levels of oxygen provided by HBOT ensures that traditional
therapies are effective by stopping the spread and reproduction of deadly
bacteria and by killing any that are present in the brain tissue.
Most of the patients treated with hyperbaric oxygen have
returned to their regular daily activity after recovery, with less apparent
brain damage. Therapy with hyperbaric oxygen carries minimal risks.
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