Skin grafting is a surgical
procedure to place skin or skin substitute over a burn or non-healing wound to
permanently replace damaged or missing skin or provide a temporary wound
dressing. Sometimes these grafts fail (or become compromised) due to poor blood
flow, swelling or infection.
Capillary proliferation,
protection from reperfusion injury, anti-edema action, rheological capillary
improvement and protection from infection are among the demonstrated effects of
hyperbaric hyperoxia.
Hyperbaric oxygen therapy
is an extremely effective therapy for tissues affected by a burn, radiation
therapy or in patients with decreased perfusion or hypoxia. Some skin grafts
(from a severe burn) or flaps (a graft which is moved and reattached along with
the blood vessel that supplies it) may have trouble healing from swelling or
poor blood flow.
Hypoxia due to inadequate
grafted tissue oxygenation, involves hyperbaric oxygen use as adjunct therapy.
·
While HBOT can help save failing grafts it can be even more
effective when used before surgery to keep grafts from failing in the first
place.
· HBOT also offers strategies for reducing edema. The edema
reduction effect, induced by the relative spasm of a precapillary arteriolar
sphincter helps to limit the swelling of the graft or flap.
The high oxygen
tension achievable with HBOT induces neovascularization. Among other things,
oxygen dissolved in plasma is readily available to tissues and organs thus
limiting damage from reperfusion injury.
The effectiveness of HBOT is shown in grafting and in
reimplantation of limbs, with a salvage rate of 75% for the HBOT group compared
to 46% for the controls, with 100% HBOT salvage when the patient is treated
within 72 hours post-operatively.
The use of HBOT for the preparation of a base for skin grafting and the preservation of compromised skin grafts has been well documented as effective. HBOT’s effectiveness in aiding skin graft survival is supported by research.
The use of HBOT for the preparation of a base for skin grafting and the preservation of compromised skin grafts has been well documented as effective. HBOT’s effectiveness in aiding skin graft survival is supported by research.
Proper
timing of hyperbaric oxygen therapy through a collaboration of the plastic
surgeon with the hyperbaric physician are considered necessary for the desired
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